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慢性阻塞性肺病(以下简称慢阻肺,COPD)患者的内分泌功能改变近年已引起注意。COPD病人合并糖尿病在临床上并不少见。为探讨COPD合并糖尿病时的临床特点及其预后,我们统计了1987年1月至1991年6月收治住院的COPD急性发作期病人412例,对同时合并糖尿病的22例患者进行了临床分析,并对部分病人进行了葡萄糖耐量试验(OGTT)、胰岛素释放试验(IRT)及胰高糖素水平观察,以初步探讨其发生机理。
Chronic obstructive pulmonary disease (hereinafter referred to as chronic obstructive pulmonary disease, COPD) changes in endocrine function has attracted attention in recent years. COPD patients with diabetes are not uncommon in clinical practice. To investigate the clinical features and prognosis of patients with COPD complicated with diabetes mellitus, 412 patients with acute exacerbation of COPD admitted to our hospital from January 1987 to June 1991 were enrolled in this study. Twenty-two patients with concurrent diabetes mellitus were analyzed clinically. Some patients were impaired glucose tolerance test (OGTT), insulin release test (IRT) and glucagon levels to explore its mechanism of onset.