2006-2014年德清县农村成人2型糖尿病患病情况及流行趋势

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目的了解2006—2014年浙江省德清县农村成人2型糖尿病(type 2diabetes mellitus,T2DM)患病现状及变化趋势,并探索其患病的影响因素。方法随机整群抽取浙江省德清县8个农村社区,以18周岁及以上户籍居民为研究对象,于2006—2008年、2011—2012年和2013—2014年分三阶段完成横断面调查,其中2006—2008年实际调查6562人,2011—2012年11 763人,2013—2014年10 904人。调查对象接受问卷调查(包括人口学、生活方式及疾病史信息)、体格检查(身高、体重、血压等)和空腹血糖测量。T2DM诊断标准为空腹血糖≥7.0 mmol/L或自报患有医生诊断的糖尿病或正在接受糖尿病治疗。结果 2006—2014年德清县农村成人T2DM及空腹血糖受损(impaired fasting glucose,IFG)患病率均呈逐年上升趋势,T2DM标化患病率依次为1.2%、1.6%和2.1%,IFG患病率分别为7.2%、18.7%和22.8%。多因素Logistic回归分析显示,高年龄(与18~39.9岁相比:调整OR(aOR)_(40-59.9岁)=5.20,95%CI 2.74~9.89;aOR_(60岁及以上)=8.02,95%CI 4.19~15.35)、女性(aOR=1.23,95%CI 1.02~1.49)、糖尿病家族史(aOR=4.86,95%CI3.49~6.77)、超重/肥胖(aOR_(超重)=1.88,95%CI 1.61~2.20;aOR_(肥胖)=5.10,95%CI 4.06~6.41)、高血压(aOR=2.84,95%CI 2.44~3.31)、荤食(与饮食荤素均衡相比:aOR=2.25,95%CI 1.89~2.69)是T2DM的独立危险因素,而饮茶(aOR_(饮茶)=0.81,95%CI 0.68~0.95)是其保护因素。结论 T2DM在德清县农村成人中流行水平较低,但呈快速上升趋势;高年龄、女性、家族史、超重/肥胖、荤食和高血压等是T2DM患病的危险因素,饮茶是保护因素。 Objective To investigate the prevalence and trend of type 2 diabetes mellitus (T2DM) in rural areas of Deqing County, Zhejiang Province from 2006 to 2014 and explore the influencing factors. Methods A total of 8 rural communities in Deqing County of Zhejiang Province were randomly selected. A total of 18-year-old and above were selected as the research objects. The cross-sectional survey was completed in three phases from 2006 to 2008, from 2011 to 2012 and from 2013 to 2014. Among them, 2006 - 6,562 actual surveys in 2008, 11,763 in 2011-2012 and 10,904 in 2013-2014. Subjects were surveyed (including demographics, lifestyle and disease history information), physical exams (height, weight, blood pressure, etc.) and fasting glucose measurements. T2DM diagnostic criteria for fasting blood glucose ≥ 7.0 mmol / L or self-reported with a doctor diagnosed diabetes or diabetes treatment. Results The prevalence of T2DM and impaired fasting glucose (IFG) in rural adults in Deqing County from 2006 to 2014 showed a trend of increasing year by year. The prevalence of T2DM was 1.2%, 1.6% and 2.1% respectively. The prevalence of IFG The rates were 7.2%, 18.7% and 22.8%, respectively. In multivariate Logistic regression analysis, high age (adjusted OR = (40-59.9 years) = 5.20, 95% CI 2.74-9.89; aOR_ (60 years and older) = 8.02 vs. 18-39.9 years) (AOR = 1.23, 95% CI 1.02-1.49), family history of diabetes (aOR = 4.86,95% CI 3.49-6.77), overweight / obesity (aOR_ 95% CI 1.61 to 2.20; aOR_ (obesity) = 5.10, 95% CI 4.06 to 6.41); hypertension (aOR = 2.84; 95% CI 2.44 to 3.31) 2.25, 95% CI 1.89-2.69) were independent risk factors for T2DM, while drinking tea (aOR_ = 0.81, 95% CI 0.68-0.95) was the protective factor. Conclusions T2DM prevalence is low in rural adults in Deqing County, but it shows a rapid upward trend. High age, female, family history, overweight / obesity, meat-eating and high blood pressure are risk factors for T2DM. Drinking tea is a protective factor .
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