患者 ,女 ,4 0岁 ,因精神分裂症而口服氯氮平 2个月后症状消失 ,自行停药 ,停药 2个月精神病症状复发 ,故收入住院。病人既往无药物过敏史 ,也无皮疹等过敏性疾病的病史。入院诊断为精神分裂症。入院后立即予以口服氯氮平进行抗精神病治疗 ,第 1天2 5ｍｇ ,第 2天 50ｍｇ ,第 3 Patients, female, 40 years old, due to schizophrenia and oral clozapine 2 months after the symptoms disappear, their withdrawal, discontinuation of psychiatric symptoms 2 months recurrence, so the income of hospitalization. In the past, the patient had no history of drug allergies and no history of allergic diseases such as rashes. Admission was diagnosed as schizophrenia. Oral clozapine was given for antipsychotic treatment immediately after admission, 25 mg on day 1, 50 mg on day 2,