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对新诊断、未曾治疗过的T2DM患者给予1～3个月短期胰岛素强化治疗,随访观察胰岛β细胞功能变化及对血糖长期控制的影响。结果β细胞功能获得显著改善(P<0.01);停药后血糖维持稳定3月-3年不等。结论对新诊断T2DM患者短期胰岛素强化治疗能显著改善胰岛β细胞功能。
The newly diagnosed and untreated T2DM patients were given 1 to 3 months of short-term insulin-intensive therapy. The changes of islet β-cell function and long-term control of blood glucose were observed. Results β-cell function was significantly improved (P <0.01); after stopping the blood glucose remained stable in March - 3 years. Conclusion Short-term intensive insulin treatment of newly diagnosed T2DM patients significantly improves pancreatic β-cell function.