目的探讨并比较腹腔镜根治术和传统开腹手术治疗结肠癌患者的临床疗效。方法选取我院在2011年1月至2014年1月收治的结肠癌患者60例,随机分为观察组和对照组,对照组行传统开腹手术治疗,观察组行腹腔镜根治术,并比较两组疗效。结果两组患者在手术时间以及淋巴结清扫数目方面的比较无明显差异(P>0.05),但是观察组的术中出血量、术后排气时间、住院时间以及术后并发症发生率均明显小于对照组(P<0.05)。结论与传统开腹手术比较,腹腔镜根治术治疗结肠癌具有创伤小、恢复快、并发症少等优势,且疗效显著。 Objective To investigate and compare the clinical efficacy of laparoscopic radical mastectomy and traditional laparotomy in patients with colon cancer. Methods Sixty patients with colon cancer admitted to our hospital from January 2011 to January 2014 were randomly divided into observation group and control group. The control group received conventional laparotomy and the observation group underwent laparoscopic radical mastectomy. Two groups of curative effect. Results There was no significant difference between the two groups in the operation time and the number of lymph node dissection (P> 0.05). However, the intraoperative blood loss, postoperative exhaust time, hospital stay and postoperative complications were significantly lower in the observation group than in the observation group Control group (P <0.05). Conclusion Compared with traditional laparotomy, laparoscopic radical mastectomy has the advantages of less trauma, faster recovery and fewer complications, and has a significant curative effect.