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为了评价依托泊甙(鬼臼乙叉甙)在最大剂量200 mg/m~2,单独用来治疗食管癌的作用,对26名晚期或转移性食管鳞癌病人进行了治疗。他们平均年龄57岁(42～77岁),其中13人先前做过食管切除术,6人接受过放疗。具体方法为,依托泊甙200 mg/m~2加入250～500 ml生理盐水中,在30～60 min内静脉输入,连续3日。每3周重复一次。对于治疗后病情改善或无变化者,最多给予6个疗程。治疗后恶化或不能耐受毒性作用者,则停止治疗。恶性肿瘤的所有表现皆消失至少4周,为完全有效;所有病灶的二正交直径积的总和减少50％,并无新病灶者为部分有效;小
In order to evaluate the effect of etoposide (Erythropoietin) at a maximum dose of 200 mg/m 2 , used alone to treat esophageal cancer, 26 patients with advanced or metastatic esophageal squamous cell carcinoma were treated. Their average age was 57 years (42-77 years), of whom 13 had previously performed esophageal resection and 6 had received radiotherapy. The specific method is: Etoposide 200 mg/m~2 is added into 250~500 ml normal saline, intravenously in 30~60 min, for 3 consecutive days. Repeat every 3 weeks. For those who have improved or no change after treatment, up to six courses are given. People who have worsened or are unable to tolerate toxic effects after treatment will stop treatment. All manifestations of malignant tumors disappeared for at least 4 weeks and were completely effective; the sum of the two orthogonal cross-products of all lesions was reduced by 50%, and no new lesions were partially effective;