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作者将肺阻抗血流图与右心收缩时间间期相结合,建立了无创伤测定肺血管顺应性的方法,即 C_(PA)=0.034t/[RPEP/RVET·In(Ho/Ht)]+0.017(L/kPa),C_(IP)=0.063t/[RPEP/RVET.In(Ho/Ht)]+0.006(L/kPa)。对21例慢性阻塞性肺病(COPD)患者测定结果表明平静时肺动脉高压组(11例)C_(PA)和 C_(TP)均显著低于压力正常组(10例),C_(PA) 和 C_(TP)与 P_(PA)及 PAR(或 TPR)呈负曲线关系,提示随着病变加重,肺血管顺应性不断下降;两组运动时肺循环阻力基本不变而顺应性显著降低,说明运动致血管壁张力增高;本法比 Reuben 法及王迪浔法简便、易推广。
The authors established a non-invasive method for the determination of pulmonary vascular compliance by combining the pulmonary impedance blood flow map with the right ventricular contraction time interval, C_ (PA) = 0.034 t / [RPEP / RVET · In (Ho / Ht)] +0.017 (L / kPa), C_ (IP) = 0.063 t / [RPEP / RVET.In (Ho / Ht)] + 0.006 (L / kPa). The results of 21 patients with chronic obstructive pulmonary disease (COPD) showed that the levels of C_ (PA) and C_ (TP) in pulmonary hypertension group were significantly lower than those in normal pressure group (n = 10), C_ (TP) and P_ (PA) and PAR (or TPR) showed a negative curve, suggesting that as the lesion aggravated, pulmonary vascular compliance continued to decline; exercise resistance of pulmonary circulation basically unchanged while the compliance was significantly reduced, indicating exercise induced Vascular wall tension increased; this method than the Reuben method and Wang Di 浔 simple, easy to promote.