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我们对30名正常人和30名高血压病患者分别做了握力试验(增加心脏后负荷)和硝酸甘油试验(降低前负荷)后的多普勒左室舒张功能指标测定。结果显示:高血压病组与正常对照组相比,二尖瓣血流频谱心房收缩期峰值流速(VA)及流速积分(TVIA)升高;舒张早期峰值流速(VE)及流速积分(TVIE)无明显差异,E/A及TVLE/TVIA降低。握力试验对正常人和高血压病组的左室舒张功能指标的影响均为:VE、E/A、TVIE、TVIE/TVIA降低,VA及TVIA升高。硝酸甘油降低心脏前负荷后对两组的影响
We measured the Doppler left ventricular diastolic function in 30 normal subjects and 30 hypertensive patients after performing the grip test (increasing post-cardiac load) and nitroglycerin test (decreasing pre-load) respectively. The results showed that the peak flow velocity (VA) and the velocity integral (TVIA) of atrial systolic mitral flow were significantly increased in hypertensive patients compared with those in the normal control group; peak early diastolic velocity (VE) and velocity integral (TVIE) No significant difference, E / A and TVLE / TVIA decreased. The effect of grip test on left ventricular diastolic function in both normal and hypertensive patients was VE, E / A, TVIE, TVIE / TVIA decreased, VA and TVIA increased. Nitroglycerin reduces the effect of pre-cardiac load on both groups