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目的 探讨原发性纵隔神经源性肿瘤的临床病理特征和外科治疗原则。方法 总结125 例纵隔神经源性肿瘤的诊治经验。所有病例均经手术和病理证实。结果 神经源性肿瘤占同期原发性纵隔肿瘤及囊肿的22 .0 % (125/568) 。其中神经鞘瘤48 .9 % (61/125) ,神经纤维瘤27 .2 % (34/125) ,节细胞神经瘤13 .6 % (17/125) ,其他少见肿瘤10 .4 % (13/125) 。无临床症状而于查体时发现78例,占62 .4 % 。肿瘤位于后纵隔117 例。手术切除率98 .4 % (123/125) ,术后并发症发生率4 .0 % (5/125) ,手术死亡率0 .8 % 。恶性肿瘤的3 年生存率18 .2 % 。结论 纵隔神经源性肿瘤的临床特征与病理类型相关,无论良恶性均首选手术治疗,不同的病理类型有不同的预后。
Objective To investigate the clinicopathological characteristics and principles of surgical treatment of primary mediastinal neurogenic tumors. Methods The diagnosis and treatment experience of 125 mediastinal neurogenic tumors was summarized. All cases were confirmed by surgery and pathology. Results Neurogenic tumors accounted for 22.0% (125/568) of primary mediastinal tumors and cysts at the same time. Among them, 48.9% (61/125) of schwannomas, 27.2% (34/125) of neurofibromas, 13.6% (17/125) of ganglioneuromas, and 10.4% (13%) of other rare tumors. /125). 78 cases were found in the examination without clinical symptoms, accounting for 62.4%. The tumor was located in 117 cases of posterior mediastinum. The surgical resection rate was 98.4% (123/125), the postoperative complication rate was 4.0% (5/125), and the surgical mortality rate was 0.8%. The 3-year survival rate of malignant tumors is 18.2%. Conclusions The clinical features of mediastinal neurogenic tumors are related to pathological types. Surgical treatment is the first choice for both benign and malignant patients. Different pathological types have different prognosis.