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目的探讨多索茶碱联合可必特治疗支气管哮喘急性发作的临床效果。方法选取2012年10月—2013年10月息县人民医院收治的支气管哮喘急性发作患者96例,按随机分层法将患者分为观察组与对照组,各48例。对照组患者在基础治疗基础上予以氨茶碱联合沙丁胺醇治疗,观察组患者在基础治疗基础上予以多索茶碱联合可必特治疗。观察两组患者临床疗效及不良反应发生情况。结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论多索茶碱联合可必特治疗支气管哮喘急性发作的临床效果好,不良反应少。
Objective To investigate the clinical efficacy of doxofylline combined with cortisone in the treatment of acute exacerbation of bronchial asthma. Methods Ninety-six patients with acute exacerbation of bronchial asthma were selected from Xixian People’s Hospital from October 2012 to October 2013. The patients were divided into observation group and control group according to randomized stratification method, 48 cases in each group. Patients in the control group were treated with aminophylline combined with albuterol on the basis of basic treatment. The patients in the observation group were treated with doxofylline and mayoride on the basis of basic treatment. The clinical efficacy and adverse reactions of the two groups were observed. Results The total effective rate of observation group was higher than that of control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions (P> 0.05). Conclusion Doxofylline combined with bebital in the treatment of acute exacerbation of bronchial asthma has good clinical effect and few adverse reactions.