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Roberts制药公司的丙毗兰（propiram，商品名Dirame）的Ⅲ期临床研究数据的初步分析表明，本品对治疗术后牙痛有效。350例摘除两颗或两颗以上第三磨牙的病人随机口服本品25，50，100或150mg，或曲马多（tramadol，商品名Ultram）100mg或安慰剂。与基准疼痛强度相比，接受本品50
A preliminary analysis of phase III clinical data from Roberts Pharmaceuticals’ propiram (trade name Dirame) shows that this product is effective in treating post-operative toothache. 350 patients with two or more third molars were randomized to receive either 25, 50, 100 or 150 mg of the product or 100 mg of tramadol (trade name Ultram) or placebo. Compared with the baseline pain intensity, to accept this product 50