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目的:探讨鼻唇沟折叠皮瓣在鼻翼洞穿缺损修复中的临床应用.方法:回顾性研究我院2014 年1 月～2018年6月应用鼻唇沟折叠皮瓣修复鼻翼肿瘤切除后形成的穿洞缺损23例,并观察其疗效.结果:23例患者皮瓣全部存活,术后随访6个月至3年,瘢痕不明显,鼻翼形态基本对称、无臃肿,鼻孔无狭窄,缺损修复处皮肤感觉功能保存,患者术后满意.结论:鼻唇沟皮瓣易成活、血运丰富,能提供足够组织从而对鼻翼洞穿缺损进行修复,并且转移灵活、血管蒂长,为修复鼻翼洞穿缺损良好皮瓣之一.“,”Objective: To discuss the clinical application of nasolabial fold flap in repairing through-and-through defects of the nasal ala. Methods: A retrospective study was conducted on 23 cases of through-and-through defects after resection of alae nasi malignant with nasolabial fold flap in our hospital from January 2014 to June 2018, and its clinical effect was ob-served. Results: All the 23 flaps survived. The follow-up period ranged from 6 months to 3 years. The scar was not obvious. The shape of ala nasi was symmetrical without swelling. The nostrils were not narrow. The sensory function of the skin in the repaired defect site was maintained. Patients were satisfied with the operation. Conclusion: The nasolabial fold flap with long vascular pedicle, which can be easily transferred, is easy to survive and has abundant blood supply. It can provide e-nough tissue to repair the through-and-through defects of the nasal ala. It serves as one of the good flaps for repairing the through-and-through defects after resection of alae nasi.