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去细胞基质在组织工程及再生医学的大量应用为解决组织器官的修复和重建等难题带来了希望。去细胞方法大致可以分为三类:化学处理法、物理处理法及酶学处理法,且已经应用于组织工程及再生医学的各个方面。本文总结并分类目前常用的去细胞方法及其在组织工程各方面的应用,对目前国内外常用的去细胞方法及其在组织工程及再生医学中的应用进行回顾总结与分析。
A large number of applications of acellular matrix in tissue engineering and regenerative medicine have brought hope for solving the problems of tissue organ repair and reconstruction. Cell-free methods can be roughly divided into three categories: chemical treatment, physical treatment and enzymatic treatment, and have been applied in all aspects of tissue engineering and regenerative medicine. This article summarizes and classifies the current commonly used acellular method and its application in all aspects of tissue engineering. It reviews and analyzes the commonly used acellular methods and its applications in tissue engineering and regenerative medicine at home and abroad.