1954年R.A.Good首次报道了1例患有胸腺瘤及低丙种球蛋白血症的成年患者,2年后又对这类患者的免疫反应进行临床及实验研究,发现患者有免疫功能缺陷,之后学者将这类患者称之为Good’s综合征。90年代后研究者发现该类患者有B淋巴细胞产生分化障碍,T淋巴细胞功能低下,属于原发性免疫缺陷病。 In 1954, RAGood first reported an adult patient with thymoma and hypogammaglobulinemia. Two years later, the clinical and experimental studies on the immune response of these patients showed that the patients had immune deficiency. Afterwards, scholars These patients are called Good’s syndrome. After the 1990s researchers found that such patients have B lymphocyte differentiation disorders, T lymphocyte dysfunction, is a primary immune deficiency disease.