目的了解口服药物方式与食管溃疡的关系。方法回顾性分析经胃镜检查存在口服药物致食管溃疡患者的临床资料、胃镜所见和病理表现。结果口服药物方式不当可致食管溃疡,大多发生于食管中段,溃疡表浅,形态规则,边缘规整。结论口服药物方法不当可造成食管溃疡。 Objective To understand the relationship between oral medication and esophageal ulcer. Methods The clinical data, endoscopic findings and pathological findings of patients with esophageal ulcer caused by oral medication underwent endoscopy were retrospectively analyzed. The results of oral medication improper manner can cause esophageal ulcers, mostly in the middle of the esophagus, superficial ulcers, regular rules, the edge of the orderly. Conclusion Improper oral medication can cause esophageal ulcer.