闭锁综合征(locked-in syndrome,LIS)又称去传出状态,系脑桥基底部病变所致,是临床上不太常见的一种特殊意识状态,死亡率高,早期常被误诊,如能早期确诊并治疗,则可大大提高患者生存率。目前影像学检查则成为诊断LIS早期诊断最重要的手段,现将本院诊断的2例LIS患者早期影像学表现报告如下并加以讨论,以提高对本病的诊断及鉴别诊断的水平。例1女,31岁。晨起小便后出现完全不能发音,四肢 Lock-in syndrome (LIS), also known as the outgoing state, is caused by the lesion of the base of the pontine, which is a less common clinical state of special consciousness with high mortality and early misdiagnosis. Early diagnosis and treatment, can greatly improve patient survival. At present, imaging examination has become the most important means to diagnose the early diagnosis of LIS. The imaging findings of 2 cases of LIS diagnosed in our hospital are reported as follows and discussed in order to improve the diagnosis and differential diagnosis of this disease. Example 1 Female, 31 years old. Appeared early after urination can not pronounce, limbs