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作者分析Morristown纪念医院开展~(111)铟-8-羟基喹啉(oxine)标记自体白细胞的扫描方法最初6个月中(1982年12月至1983年6月)18个病例的资料,总结此法在结、直肠感染性并发症及结肠炎性病变中的应用。扫描操作程序如下:用肝素化的注射器抽血50ml送至实验室,以大约500μCi的放射性铟标记白细胞后在3小时内注入病人体内,并在4~18小时以后用γ照相机从头顶至臀部以下作前位及后位扫描。临床上如有需要,也可作四肢扫描。每次显像收集30万次计数。在11例结、直肠疾病中施行了12次扫描,结果11次阳性(不正常)。仅1次扫描阴性(正常),患者经探腹和结肠造瘘后腹部切口有蜂窝织炎,未形成脓肿,患者对标记的白细胞发生过敏反应,表现为潮红及哮喘。4
The authors analyzed data from 18 cases from the first 6 months (December 1982 to June 1983) of scanning methods for the preparation of autologous leukocytes labeled with (111) indium-8- hydroxyquinoline by Morristown Memorial Hospital. The application of the method in the complications of infection of the rectum, rectum and colitis. The scanning procedure was as follows: Heparinized syringes were used to deliver 50 ml of blood to the laboratory, leucocytes were labeled with approximately 500 μCi of radioactive indium and injected into the patient within 3 hours, and from 4 to 18 hours later with a gamma camera from head to hip For front and rear scans. Clinically, if necessary, it can also be used for limb scanning. Each shot collects 300,000 counts. Twelve scans were performed in 11 cases of rectal and rectal diseases and the results were 11 positive (abnormal). Only one scan was negative (normal). The patient had cellulitis after abdominal exploration and colostomy. Abscess was not formed and the patient developed an allergic reaction to the marked white blood cells, manifested as flushing and asthma. 4