美国学者Wenger等通过对MARISA,CARISA,RAN080和ERICA四项大型临床研究进行汇总分析发现,虽然在运动平板试验评价的雷诺嗪治疗患者中女性改善程度较小,但是在改善心绞痛发作频率和服用硝酸甘油患者中,雷诺嗪治疗没有性别差异,而且安全性好,提示雷诺嗪是一个安全而且有效的抗心 A summary of four large-scale clinical studies of MARISA, CARISA, RAN080 and ERICA by American scholar Wenger et al found that although there was less improvement in women with ranolazine in the treadmill test, the improvement in the frequency of angina attacks and the use of nitric acid In patients with glycerin, ranolazine treatment without gender differences, and good safety, suggesting that ranolazine is a safe and effective anti-heart