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我国是一个中药提取物的生产大国。中药提取物已被广泛用于药品、保健品、化妆品等多个领域。但是,对于中药提取物的毒理研究并不多,很多中药提取物的LD50数据无法获得,从而导致毒理学安全性评价的困难。本文对近期完成的白前(Rhizoma CynanchiStauntonii)和合欢皮(Cortex Albiziae)提取物急性毒性试验研究进行了汇总,旨为深入研究提供初步的安全性评价资料。
China is a large producer of Chinese herbal extracts. Chinese medicine extract has been widely used in medicine, health products, cosmetics and other fields. However, there are not many toxicological studies on extracts of traditional Chinese medicine, and LD50 data of many traditional Chinese medicine extracts are not available, which leads to the difficulty of toxicological safety assessment. In this paper, the recent studies on the acute toxicity of Rhizoma Cynanchi Tautonii and Cortex Albiziae extracts were summarized to provide preliminary information on safety evaluation.