目的　研究沿淮灾区钩端螺旋体病特征 ,为预防灾后钩端螺旋体病爆发流行提供依据。方法　血清学检测采用MAT法 ,动物抗原检测采用RT -PCR ,病原学应用柯索夫培养基分离。结果　沿淮灾区钩端螺旋体病血清群以黄疸出血群为主 ,占 83.33% ,与 2 0世纪 70年代相比出现南黄北移现象。其中怀远县阳性率最高 ,为 1 0 .34%。鼠密度为 8.88% ,带菌率为 2 5 .0 0 %。结论　沿淮灾区钩端螺旋体病以黄疸出血群为主 ,病死率高 ,应引起足够的重视 ,同时要采取灭鼠、预防接种及应急性口服强力霉素等预防措施 Objective To study the characteristics of leptospirosis in the disaster areas along the Huaihe River and provide a basis for preventing the outbreak of post-disaster leptospirosis. Methods The serological test was performed by MAT method. The animal antigens were detected by RT-PCR and the etiology was detected by using Kosov’s medium. Results The leptospirosis serogroups in the Huaihe area were dominated by hemorrhagic jaundice, accounting for 83.33%. Compared with the 70s in the 20th century, the phenomenon of southward yellowing shifted northward. Which Huaiyuan County, the highest positive rate of 10.34%. The rat density was 8.88% and the carrier rate was 25.0%. Conclusion Leptospirosis in the areas along the Huaihe River coast is dominated by hemorrhagic jaundice and its mortality is high, which should be given sufficient attention. At the same time precautionary measures should be taken such as deratization, vaccination and oral administration of doxycycline