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目的:对胸部肿瘤以致异位ACTH综合征进行分析,找到其临床特点及有效的治疗方式,进以提高其治疗水平,促进医学发展。方法:通过对2003年2月至2012年3月我院确诊并收治的胸部肿瘤致异位ACTH综合征的9例患者治疗过程及临床病状进行分析整理,确定胸部肿瘤致异位ACTH综合征临床特点,同时分析其治疗方式,找到最佳治疗方案。结果:我院确诊并收治的9例患有异位ACTH综合征的患者,其主要临床病征为,低血钾、高血压等现象,部分病人出现水肿现象。采用胸腺类癌及支气管类癌手术进行切除对治疗异位ACTH综合征有一定的效果,对小细胞肺癌合并异位ACTH综合征患者进行治疗过程中,应首选化疗方式,但是采用化疗进行治疗效果虽然优于其他方式,可是预后效果却不理想。结论:胸部肿瘤极容易引发异位ACTH综合征出现,在患病过程中如果患者出现低血钾、高血压或水肿等症状的患者就极有可能出现异位ACTH综合征。
OBJECTIVE: To analyze the ectopic ACTH syndrome in thoracic tumors so as to find out its clinical characteristics and effective treatment methods, in order to improve its therapeutic level and promote the development of medicine. Methods: From February 2003 to March 2012 in our hospital diagnosed and admitted to the thoracic tumor induced ectopic ACTH syndrome in 9 patients with treatment and clinical symptoms were analyzed and sorted to determine the chest tumor ectopic ACTH syndrome clinical Characteristics, at the same time analyze the treatment, find the best treatment. Results: Nine patients with ectopic ACTH syndrome diagnosed and treated in our hospital had the main clinical symptoms of hypokalemia and hypertension, and some patients had edema. The use of thymic carcinoid and bronchial carcinoid resection for the treatment of ectopic ACTH syndrome have some effect on patients with small cell lung cancer combined with ectopic ACTH syndrome should be the preferred chemotherapy, but the use of chemotherapy for treatment Although superior to other ways, but the prognosis is not satisfactory. CONCLUSIONS: Thoracic tumors are highly likely to cause ectopic ACTH syndrome, and patients with symptoms of hypokalemia, hypertension, or edema are most likely to develop ectopic ACTH syndrome during the illness.