联合检测血清CA72-4、CA19-9和CEA对胃癌临床价值的探讨

来源 :中国肿瘤临床 | 被引量 : 0次 | 上传用户:dabingjiajia
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的:探讨血清CA72-4、CA19-9、CEA联合检测对胃癌的临床价值。方法:对32例中晚期胃癌患者和21例良性胃病患者采用放射免疫法(RIA)分别测定CA72-4、CA19-9和CEA。结果:胃癌组中CA72-4、CA19-9、CEA血清测定值水平、阳性率均明显高于良性胃病组(P < 0.01。其中胃癌组的CA72-4阳性率(59.4%明显高于CA19-9和CEA28.1%。联合检测时胃癌组中各种联合方式阳性率均明显高于良性胃病组,且良性胃病组阳性率不增加,其中胃癌组的联合检测CA72-4+CA19-9、CA72-4+CA19-9+CEA阳性率分别提高到68.8%和71.8%,均明显高于其他联合方式,如CA72-4+CEA(46.8%)、CA19-9+CEA(43.8%。但CA72-4+CA19-9和CA72-4+CA19-9+CEA之间无统计学差异(P >0.05。结论:以CA72-4+CA19-9或CA72-4+CA19-9+CEA联合检测可以提高胃癌的阳性检出率,但不增加良性胃病假阳性率,故对胃癌的早期诊断、疗效监测、预后、复发转移有重要意义。 Objective: To explore the clinical value of combined detection of serum CA72-4, CA19-9 and CEA in gastric cancer. METHODS: CA72-4, CA19-9, and CEA were measured by radioimmunoassay (RIA) in 32 patients with advanced gastric cancer and 21 patients with benign gastropathy. Results: The serum levels of CA72-4, CA19-9 and CEA in the gastric cancer group were significantly higher than those in the benign gastropathy group (P < 0.01). Among them, the CA72-4 positive rate in the gastric cancer group (59.4%).  Significantly higher than CA19-9 and CEA28.1%.The positive rates of various combinations in the gastric cancer group were significantly higher than those in the benign gastropathy group when combined detection, and the positive rate of the benign gastropathy group did not increase, including the combination of gastric cancer groups. The positive rates of CA72-4+CA19-9 and CA72-4+CA19-9+CEA were increased to 68.8% and 71.8%, respectively, which were significantly higher than other combinations, such as CA72-4+CEA (46.8%) and CA19-9+CEA ( There was no statistical difference between CA72-4+CA19-9 and CA72-4+CA19-9+CEA (P>0.05 ).Conclusion: Take CA72-4+CA19-9 or CA72-4+CA19-9+C. A joint detection can improve the positive rate of gastric cancer, but benign stomach without increasing the false positive rate, so early diagnosis of gastric cancer, the efficacy of monitoring, prognosis, recurrence is important.
其他文献
本文对食管癌的瘤周切除范围进行研究,认为食管癌复发的原因是多方面的。因此,应重视食管癌术后的综合治疗,以减少复发,改善疗效。1 材料与方法1.1 对象 为1996年1月至1999年12月间手术治疗的
濮阳市位于河南省东北部,降水稀少,属比较干旱地区。近年来,随着社会经济发展与城市化进程的加快,濮阳市用水总量呈逐年上升的趋势。但水资源短缺与浪费现象严重,水资源供需
头痛即指由于外感与内伤,致使脉络绌急或失养清窍不利所引起的以患者自觉头部疼痛为特征的一种常见病征,也是一个常见症状.可以发生在多种急慢性疾病中.有时亦是某些相关疾病
期刊
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生、测量监控等方面人手,介绍了S226海滨大桥
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生、测量监控等方面人手,介绍了S226海滨大桥
期刊
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生、测量监控等方面人手,介绍了S226海滨大桥
目的:研究欧必亭对原发性肝癌介入治疗所致恶心呕吐的预防作用。方法:1 000例原发性肝癌患者行介入治疗,600例于介入治疗前动脉内注射欧必亭5mg,对照组400例患者未用欧必亭等5-羟色胺(5-HT3)受体拮抗剂
期刊