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本研究选用实验动物长爪沙鼠和小白鼠拟建立新的人蛲虫病动物模型。在实验前，全部动物用复方甲苯咪唑（８０ｍｇ／ｋｇ）驱除肠道线虫。感染动物的蛲虫卵，一种直接取自蛲虫病患儿肛门处，另一种为实验室培养的雌性蛲虫成虫产的卵。实验组动物分别以不同数量的虫卵（１００个／只、４００个／只和１０００个／只）经口感染并分组喂养。同时在小白鼠的实验组中，选一组肌注醋酸可的松。１～４周后分批解剖动物从肠道收集蛲虫，结果所有动物均未发现蛲虫。本实验结果表明，长爪沙鼠和小白鼠对人蛲虫不具有易感性。这种不易感性与感染动物的虫卵数量、获取虫卵的方法及动物的免疫状态无关。
In this study, we selected the experimental animals Mongolian gerbils and mice to establish a new human enterobiasis animal model. Before the experiment, all animals were driven by compound mebendazole (80 mg / kg) to eradicate intestinal nematodes. Infected animal eggs, an egg directly from the anus of enterobiasis, and the other is an egg produced by a lab-grown female pinworm. The experimental animals were orally infected with different numbers of eggs (100 / only, 400 / only and 1000 / only) and fed in groups. At the same time in mice experimental group, choose a group of intramuscular cortisone acetate. After 1 to 4 weeks, the animals were collected in batches from the intestine in batches, and no pinworm was found in all the animals. The results of this experiment show that gerbil and mouse are not susceptible to human pinworm. This insensitivity is not related to the number of eggs infected with the animal, the method of obtaining the egg and the immune status of the animal.