目的 :应用示波极谱法测定诺氟沙星的含量。方法 :诺氟沙星在pH 6 .0～ 8.5的缓冲溶液及pH 7.0的电解质溶液中 ,于 - 1.0V(υsAg/AgCl)附近有一还原峰 ,测定线性范围为1.6 0× 10 -8～ 1.2 5× 10 -7mol·L-1,r =0 .9992 ,检测下限为 7.0×10 -9mol·L-1。结果 :平均回收率为 98.9% ,RSD为 0 .5 %。测得样品含量符合药典规定。结论 :本法灵敏度高 ,选择性好 ,结果准确 Objective: To determine the content of norfloxacin by oscillopolarography. Methods: Norfloxacin had a reduction peak near-1.0V (υsAg / AgCl) in buffer solution of pH6.0 ~ 8.5 and electrolyte solution of pH7.0, and the linear range was 1.6 × 10 -8 ~ 1.2 5 × 10 -7 mol·L-1, r = 0.9992, the detection limit was 7.0 × 10 -9 mol·L-1. Results: The average recovery was 98.9% with a RSD of 0.5%. Measured sample content in line with Pharmacopoeia regulations. Conclusion: This method has high sensitivity, good selectivity and accurate result