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目的评价肝动脉化疗栓塞及Ｂ超引导下注射３２Ｐ－胶体、无水乙醇（ＰＥＩ）综合序贯介入治疗原发性肝癌的临床价值。方法 ５１例中晚期肝癌分为 ２组， ２３例综合序贯应用 ＴＡＣＥ＋３２Ｐ＋ ＰＥＩ治疗， ２８例单纯应用 ＴＡＣＥ治疗。结果综合序贯组肿瘤缩小率、肿瘤完全坏死率、ＡＦＰ下降率分别为９１．２９％、８０．００％、８７．５％，而单纯ＴＡＣＥ组分别为３９．２７％、３０．４３％、４１．４６％，两组比较有显著性差异（Ｐ＜０．０１）。０．５、１、２、３年生存率综合序贯组分别为９５．６５％．８６．９５％、５６．５２％、２０．７３％，而单纯ＴＡＣＥ组分别为６４．２８％、３９．２８％、１７．８５％、００．００％（Ｐ＜０．０１）。结论ＴＡＣＥ＋３２Ｐ＋ＰＥＩ的综合序贯介入治疗是提高中晚期原发性肝癌患者生存率的有效方法。
Objective To evaluate the clinical value of hepatic arterial chemoembolization and B-guided injection of 32P-colloid and absolute ethanol (PEI) in the sequential interventional treatment of primary liver cancer. Methods Totally 51 cases of advanced hepatocellular carcinoma were divided into two groups. TACE + 32P + PEI was used in 23 cases and TACE was used in 28 cases. Results The rates of tumor shrinkage, complete tumor necrosis and AFP were 91.29%, 80.00% and 87.5% respectively in the sequential group, compared with 39.27% and 30.43% in the simple TACE group, 41.46%, there was a significant difference between the two groups (P <0.01). 0, 5, 1, 2, 3-year survival rates were 95.65% for the sequential group. 86.95%, 56.52% and 20.73% respectively, while those in the pure TACE group were 64.28%, 39.28%, 17.85% and 00.00% respectively (P <0.01). Conclusion TACE + 32P + PEI integrated sequential intervention is an effective method to improve the survival rate of patients with primary liver cancer in the late stage.