汞合金是应用最广泛的齿科充填材料之一。就其不良反应而论,除偶然出现美观的问题外,没有显著的不良作用。但在偶然的情况下,确实能产生变态反应。某些病例严重到必须避免在充填操作中应用汞合金,甚至必须去除已存在的汞合金充填物。这些反应常常累及皮肤。典型的表现是,在面部和上肢屈侧出现荨麻疹或红色斑疹,然后发展成皮炎,损害通常持续10至14天。大量的病例是妇女。水肿及苔癣样的皮疹也有报告。在口腔粘膜上看到的损害形式是丘疹,水肿,红斑及糜烂等,但一般很少出现。根据Djerassi和Berova的看法,这种 Amalgam is one of the most widely used dental filling materials. In terms of their adverse reactions, there is no significant adverse effect except for the occasional aesthetic problem. But in accidental circumstances, can really produce allergies. Some cases are so serious that the application of amalgam must be avoided during the filling operation, and even the existing amalgam fillings must be removed. These reactions often involve the skin. A typical manifestation is the presence of urticaria or red rash on the face and upper limb flex and then into dermatitis, which usually lasts for 10 to 14 days. A large number of cases are women. Edema and lichen-like rash are also reported. The forms of damage seen on the oral mucosa are papules, edema, erythema and erosions, but are seldom seen. According to Djerassi and Berova, this