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目的:探讨无症状的体内结核活动与妇科疾病的关系。方法:运用单向免疫扩散法(SRHD)检测5O例不同妇科疾患患者血清中活动性结核标志物(ATB-M),并根据不同治疗方法对(ATB-M)阳性者增加抗痨治疗及随访。结果:18例子宫肌瘤病人中94.4％ATB-M阳性(P<0.01),10例卵巢囊肿病人中80％ATB—M阳性(P<0.01),手术加抗痨治疗3个月后,ATB—M转阴率分别为100%和87.5％。9例非妇科病理性疾病患者中无1例ATB—M阳性发现。5例结核性盆腔炎中ATB-M均为阳性,对症加抗痨治疗3个月后无1例转阴。结论:本实验中大部份病人在患妇科病的同时体内有不易察觉的结核感染存在。持续、少量的结核菌感染或许是某些妇科疾病的发病诱因。
Objective: To investigate the relationship between asymptomatic tuberculosis and gynecological diseases in vivo. Methods: Serum active tuberculosis markers (ATB-M) in 50 patients with different gynecological diseases were detected by one-way immunodiffusion (SRHD) and anti-tuberculosis therapy and follow-up were performed according to different treatment methods . Results: 94.4% ATB-M was positive in 18 cases of myoma of uterus (P <0.01), and 80% of ATB-M was positive in 10 cases of ovarian cyst (P <0.01) -M negative conversion rates were 100% and 87.5%. None of the 9 patients with pathological gynecological diseases found positive ATB-M. 5 cases of tuberculous pelvic inflammatory disease ATB-M were positive, symptomatic plus anti-tuberculosis treatment after 3 months without a negative. Conclusion: In this experiment, most of the patients with gynecological diseases are not aware of tuberculosis infection in vivo at the same time. Continued, a small amount of Mycobacterium tuberculosis infection may be the cause of some gynecological diseases.