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纸型剂是近年来新出现的药物剂型,在国外已应用的比较普遍,国内也已逐渐应用。纸型剂适用于口服剂量较小、容易吸收的药物,可以节省大量辅料,如淀粉、糖衣、胶囊等。尤其是需要快速溶解收效的药物,如舌下含剂,采取纸型剂更加便当。一般纸型剂的制作,采取可溶性滤纸或经羧甲基化处理的一般滤纸,将药物吸附在上面,然后再涂上一层硬脂酸即成。洋金花是近年我国中西医结合研究的有效药物,含有以东莨菪碱为主的复合生物碱。临床应用于胃痛(消化性溃疡,慢性胃炎,胃痉挛等)、支气管喘息皆有效。尤其是在精神病科,自1970年以来,逐渐在许多医院开展洋金花合并安适剂治疗,取得了比较满意的效果。但以前应用的洋金花剂型多是以针剂、冲剂、浸剂为主,还未见有纸型剂应用的报导。洋金花系属毒麻药一类,通常一次量在一毫克左右。
Paper-based agents are new types of pharmaceutical formulations that have emerged in recent years. They have been applied in foreign countries and are gradually applied in China. Paper-type agents are suitable for oral administration of small doses of drugs that are easy to absorb, and can save a lot of accessories, such as starch, icing, capsules and so on. In particular, it is necessary to rapidly dissolve the resulting drug, such as a sublingual agent, and it is more convenient to use a paper type agent. The general paper type agent is prepared by adopting soluble filter paper or general carboxymethylated filter paper, adsorbing the drug thereon, and then applying a layer of stearic acid. Yang Jinhua is an effective drug for the study of integrated Chinese and Western medicine in recent years. It contains a compound alkaloid based on scopolamine. Clinical application for stomach pain (peptic ulcer, chronic gastritis, stomach cramps, etc.), bronchial asthma are all effective. In particular, in the Department of Psychiatry, since 1970, Yang Jinhua has been gradually incorporated in many hospitals for the treatment of anesthesia and has achieved satisfactory results. However, most of the dosage form of formerly used yangjinhua is based on injections, granules, and infusions, and there is no report on the use of paper-based agents. The golden flower system is a type of poisonous anesthetic, usually about one milligram at a time.