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目的观察自拟健脾化浊方治疗维持性血透患者营养不良的疗效。方法60例入选患者随机分为两组，每组30例。两组均给予充分透析并给予降压药、促红细胞生成素、叶酸、铁剂、优质高蛋白饮食治疗；治疗组加服自拟健脾化浊方。观察3个月。对比治疗前后两组患者营养不良状况。结果治疗组血浆白蛋白的水平较治疗前有明显提高，血红蛋白水平亦有明显改善，MQSGA分级改善，营养状态明显好转，与对照组对比有显著性差异（P＜0.05）。结论自拟健脾化浊方是治疗维持性血透合并营养不良的有效方剂之一。“,” Objective To observe the spleen change chaotic treatment the curative effect of malnutrition in patients with maintenance hemodialysis. Methods 60 patients were randomly assigned two groups, 30 cases in each group.Both groups are adequate dialysis and blood pressure drugs, erythropoietin, folic acid, iron agent, high-quality high-protein diet therapy. Treatment group plus to suit the invigorating spleen to turbidity.Observation for 3 months.Malnutrition compared two groups of patients before and after the treatment. Results Plasma albumin levels compared with before treatment in treatment group improved obviously, hemoglobin level also have improved significantly, MQSGA grader, nutritional status improved significantly, compared with the control group with significant difference (P<0.05). Conclusion From the spleen change chaotic square is for maintenance hemodialysis patients malnutrition is one of the effective prescription.