论文部分内容阅读
目的:探讨和分析肾功能不全患者抗生素药物应用现状与干预管理措施。方法:将2014年4月~2015年4月期间舟山市妇幼保健院未实施合理用药干预之前接受临床治疗的100例肾功能不全患者作为对照组,将2015年6月~2016年6月期间实施合理用药干预之后接受临床治疗的100例肾功能不全患者作为观察组,分析两组患者的抗生素药物应用情况与干预效果。结果:观察组患者的抗生素药物使用种类、抗生素药物使用时间、抗生素药物使用费用分别为(1.12±0.32)种、(5.17±1.09)d、(614.94±325.27)元,与对照组患者的(2.45±0.76)种、(10.52±2.48)d、(2472.42±314.71)元相比较,组间差异明显(P<0.05),观察组患者的抗生素药物处方合格率(97.00%)与对照组患者(56.00%)相比较,组间差异明显(P<0.05)。结论:肾功能不全患者抗生素药物应用存在一定的不合理现象,对肾功能不全患者进行合理用药管理干预可明显提高抗生素药物的合理应用。
Objective: To explore and analyze the current situation of antibiotics in patients with renal insufficiency and intervention management measures. Methods: From April 2014 to April 2015, 100 cases of patients with renal insufficiency receiving clinical treatment before the intervention of rational medicine were implemented in Zhoushan Maternal and Child Health Care Hospital between April 2014 and April 2015 as the control group, which will be implemented from June 2015 to June 2016 100 patients with clinically treated renal dysfunction after reasonable medication intervention were taken as the observation group to analyze the antibiotic application and the intervention effect of the two groups of patients. Results: The use of antibiotics, the time of using antibiotics and the cost of using antibiotics in observation group were (1.12 ± 0.32), (5.17 ± 1.09) d, (614.94 ± 325.27) yuan, respectively, which were significantly lower than those in control group (2.45 ± 0.76), (10.52 ± 2.48) d and (2472.42 ± 314.71) yuan respectively. There was significant difference between the two groups (P <0.05). The passing rate of antibiotic prescription in the observation group (97.00%) was significantly higher than that in the control group %), The difference between groups was significant (P <0.05). CONCLUSIONS: There are some unreasonable phenomena in the application of antibiotics in patients with renal insufficiency. The reasonable administration of antibiotics in patients with renal insufficiency can obviously improve the rational use of antibiotics.