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481例急性早幼粒细胞白血病经全反式维甲酸诱导达完全缓解后,分别接受4种不同的缓解后治疗方案,经随访2~87(中位数25)个月,从Kaplan-Meier生存曲线与生存概率比较,以化疗与维甲酸交替治疗组疗效较好。3年生存概率为0.768±0.062。持续单用维甲酸维持组疗效最差。
481 patients with acute promyelocytic leukemia were treated with all-trans retinoic acid to achieve complete remission, and they received 4 different post-remission treatment regimens. After follow-up of 2 to 87 (median 25 months), survival from Kaplan-Meier survived. Compared with the survival probability, the curative effect was better in the alternating treatment group with chemotherapy and retinoic acid. The 3-year survival probability was 0.768±0.062. The sustained use of retinoic acid in the maintenance group was the worst.