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随机比较释放左旋18甲基炔诺酮的宫内节育器(LNG-IUD)和皮下埋植 Norplant-2各100例,观察使用36个月共3 100妇女月的避孕效果和可接受性。仅1例使用 LNG-IUD 者妊娠。不规则出血为终止的最常见原因,在使用的第24和36个月,因出血终止率 Norplant-2组分别为每百妇女年17.3％和26.8％,在 LNG-IUD 组均为3.3％,差异极为显著。因闭经和疼痛取器仅发生在 LNG-IUD 组。其闭经的百分率在使用的第二年底最高可达29.3％。使用的36个月中 Norplant-2组有20％～40％经期延长。97％以上的受试者对所使用的方法感到满意。
Randomly compare 100 cases of intrauterine device (LNG-IUD) and norplant-2 subcutaneously with levonorgestrel 18 and observe the contraceptive effect and acceptability of 3 100 women for 36 months. Only 1 patient who had LNG-IUD had pregnancy. The most common cause of discontinuation was irregular hemorrhage at the 24th and 36th months of use, with rates of discontinuation at Norplant-2 of 17.3% and 26.8% per 100 woman years, respectively, and 3.3% in the LNG-IUD group, The difference is extremely significant. Amenorrhea and pain-grabbing occurred only in the LNG-IUD group. The percentage of amenorrhea at the end of the second year of use up to 29.3%. The 36-month Norplant-2 group had 20% to 40% of menstrual extension. More than 97% of the subjects were satisfied with the method used.