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目的 :探讨硝苯地平联合厄贝沙坦治疗2型糖尿病合并高血压的临床疗效,并进行安全性的评价。方法 :选取2型糖尿病合并高血压患者68例,作为研究对象,将患者分为对照组和观察组,其中,对照组34例患者采用厄贝沙坦进行药物的治疗,对观察组34例患者采用硝苯地平联合厄贝沙坦的药物治疗方式,对两组患者治疗中的不良反应、血糖、血压以及患者的治疗总有效率进行比较和分析。结果 :两组患者采用不同的药物治疗方式,观察组患者的治疗总有效率为94.12%,对照组患者的治疗总有效率为76.47%,总有效率对比中,P<0.05,具有统计学意义。结论 :对于2型糖尿病合并高血压症状的患者治疗中,采用硝苯地平联合厄贝沙坦进行药物治疗,减少了不良反应的发生情况,具有良好的治疗效果,因此,可以在临床中推广应用。
Objective: To investigate the clinical efficacy of nifedipine combined with irbesartan in the treatment of type 2 diabetes mellitus complicated with hypertension and evaluate its safety. Methods: Sixty-eight patients with type 2 diabetes mellitus complicated with hypertension were selected as the study subjects. The patients were divided into control group and observation group. Among them, 34 patients in the control group were treated with irbesartan, and 34 patients in the observation group Nifedipine combined with irbesartan drug treatment, the two groups of patients treated with adverse reactions, blood glucose, blood pressure and the total effective rate of treatment were compared and analyzed. Results: The two groups of patients with different drug treatment, the observation group, the total effective rate was 94.12%, the control group, the total effective rate was 76.47%, the total effective rate, P <0.05, with statistical significance . Conclusions: Nifedipine and irbesartan are used in the treatment of type 2 diabetes mellitus patients with hypertension, which can reduce the incidence of adverse reactions and have a good therapeutic effect. Therefore, it can be widely applied in clinic .