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美国依阿华州Johnson县,人口81,717人,1981年10月突然出现大量肺炎病人。作者等于1982年2月进行了回顾性调查,结果查明从1981年9～11月共诊断肺炎43例,其中10月19～25日集中地发生25例,占3个月发病总数的58％。在病因调查中发现有29例当地居民的肺炎病人是从社会上感染的(非医院内感染),即起病前均未住院,初时常规实验室没有查出病原体。在21例可用的检材中有12例(占57％)显示有嗜肺军团杆菌感染,其中8例获得证实:6例间接荧光抗体滴度有4倍增长,滴度大于1:128,2例经肺组织直接荧光检查从
USA Iowa Johnson County, population 81,717 people, in October 1981 a sudden a large number of pneumonia patients. The authors were retrospectively surveyed in February 1982 and found that 43 cases of pneumonia were diagnosed from September to November 1981, of which 25 cases occurred intensively from October 19 to 25, accounting for 58% of the total incidence in 3 months . In the etiological investigation, 29 cases of pneumonia patients from local residents were found to be infected from the society (not hospital-wide infections). All of the patients were not hospitalized before the onset of illness, and routine pathogens were not detected in routine labs. Twelve of 21 (57%) of the 21 available samples showed Legionella pneumophila infection, of which 8 were confirmed: a 6-fold increase in the indirect fluorescent antibody titer with a titer greater than 1: 128,2 Cases of direct fluoroscopic examination from the lung tissue