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目的对肝性脊髓病4例进行分析，以期引起对该病的认识，并促进对其临床和基础的更深研究。方法对4例患者的临床资料进行分析，综合文献，简述其可能的发病机理和治疗方法。结果本文4例均为男性，发病年龄为36～48岁。均有肝硬化病史、有手术或自然形成门体静脉分流，有反复肝昏迷史。起病隐袭．缓慢进行性痉挛性截瘫，无感觉及括约肌功能障碍。肝功能损害，血氨升高，脑脊液正常，脊髓MRI正常。无特效治疗。结论本病主要的特征是在肝硬化基础上逐渐出现截瘫，无感觉、括约肌障碍。预后不良。
Objective To analyze 4 cases of hepatic myelopathy in order to arouse the understanding of the disease and to promote its clinical and basic deeper research. Methods The clinical data of 4 patients were analyzed, the literature was summarized, its possible pathogenesis and treatment methods were briefly described. Results of this article are 4 cases of men, the age of onset was 36 to 48 years old. Have a history of cirrhosis, surgery or natural formation of portal vein shunt, a history of repeated hepatic coma. Insidious onset. Slow progressive spastic paraplegia, no sensory and sphincter dysfunction. Liver damage, elevated blood ammonia, normal cerebrospinal fluid, spinal cord MRI is normal. No special treatment. Conclusion The main feature of this disease is the gradual emergence of paraplegia on the basis of cirrhosis, no sensory and sphincter disorders. Poor prognosis.