【摘 要】
:
Background:Traditional Chinese medicine (TCM) treats diseases in a holistic manner,while TCM formulae are multi-component,multi-target agents at the molecular l
【机 构】
:
Institute of Interdisciplinary Complex Research, Shanghai University of Traditional Chinese Medicine
论文部分内容阅读
Background:Traditional Chinese medicine (TCM) treats diseases in a holistic manner,while TCM formulae are multi-component,multi-target agents at the molecular level.Thus there are many parallels between the key ideas of TCM pharmacology and network pharmacology.These years,TCM network pharmacology has developed as an interdisciplinary of TCM science and network pharmacology,which studies the mechanism of TCM at the molecular level and in the context of biological networks.It provides a new research paradigm that can use mode biomedical science to interpret the mechanism of TCM,which is promising to accelerate the modeization and inteationalization of TCM.Results:In this paper we introduce state-of-the-art free data sources,web servers and softwares that can be used in the TCM network pharmacology,including databases of TCM,drug targets and diseases,web servers for the prediction of drug targets,and tools for network and functional analysis.Conclusions:This review could help experimental pharmacologists make better use of the existing data and methods in their study of TCM.
其他文献
研究了琼枝麒麟菜对富营养化海水氮磷的吸收及其对Chl a的影响。结果表明,养殖琼枝麒麟菜能有效去除富营养化海水中的可溶性无机氮(DIN)和PO4-P。对DIN的清除,72 h就达到很好
近年来,福建省房地产市场开始呈现出不稳定的状态,主要体现在总量供求失衡逐步加深、结构“三层分化”愈加明显,对福建经济稳定增长产生不利影响,追求总量与结构的供需平衡是
Background:Mammalian brain are composed of a large number of specialized cell types with diverse molecular composition,functions and differentiation potentials.
白菜型油菜是三大类型油菜之一,历史悠久,遗传资源十分丰富,有油用、菜用和饲料用的多种类型,分布广泛。在大量的种植栽培和相对独立的选育后,白菜型油菜的分类异常丰富,包括多种类型及亚种,形态上千差万别,同时具有各种优良特性,如耐贫瘠、耐干旱、抗寒性强,在一些地区具有甘蓝型油菜不可替代的作用。在利用白菜型油菜改良甘蓝型油菜多年以后,在甘蓝型油菜中出现了特定环境下遗传多样性变窄的情况。因此大范围研究白菜型
Visible light communication(VLC)is a promising solution to the increasing demands for wireless connectivity.Gallium nitride micro-sized light emitting diodes(mi
正在1987年度上海好新闻评选的会议上,听到一种说法:新闻改革也有“京派”“海派”之分。据说“京派”的新闻改革主张以思想性为主,层次深、抓大问题,敢碰群众中的难点与热
在现代社会中,小说仍然是最大众化、最社会化的文学样式之一。对于一张报纸的文艺副刊来讲,刊载精萃的小说作品,是读者的需要,也是活跃文艺副刊的重要形式。在我国,小说产生
季节性的寒流和灾害性的低温天气极大地影响了甘蔗的生产,使得甘蔗抗寒品种的选育及其抗寒机理研究受到空前重视。为了探讨抗寒性不同的甘蔗品种低温胁迫下的生理生化特性,以及
The number of biological Knowledge bases/databases storing metabolic pathway information and models has been growing rapidly. These resources are diverse in the