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中性粒细胞减少性小肠结肠炎(NE)是化疗诱发中性粒细胞减少症期间发生的腹部并发症。本文着重调查含Ara-C方案治疗血液学恶性肿瘤后NE的发生率,后果及其危险因素。本文AML137例,ALL34例,NHL28例,其他血液学恶性肿瘤12例,6年间共接受含Ara-C方案治疗461疗程,NE的诊断仅限于临床上出现腹膜炎,肠梗阻及肠出血表现。共36例(17％)发生NE其中18例为肠梗血,16例腹膜炎,6例小肠出血。
Neutropenic enterocolitis (NE) is an abdominal complication that occurs during chemotherapy-induced neutropenia. This article focuses on the investigation of Ara-C regimen in the treatment of hematological malignancies NE incidence, the consequences and risk factors. In this paper, AML137 cases, ALL34 cases, NHL28 cases, 12 cases of other hematological malignancies, received a total of 461 courses of treatment with Ara-C regimen in 6 years. The diagnosis of NE was limited to clinical manifestations of peritonitis, intestinal obstruction and intestinal bleeding. A total of 36 patients (17%) developed NE of which 18 were intestinal bleeding, 16 peritonitis and 6 small intestinal bleeding.