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心肌肌钙蛋白T(cTnT)是一种相对分子质量为39000的心肌细胞收缩器.为一菲薄的细丝状的亚单位结构,对儿童心肌损害有高度的特异性和敏感性.在心肌严重受损后3～4天,血中浓度升高,并维持此高水平6～14天.可作为急性心肌炎的血清标记物,并可能预示心肌炎的发病率和死亡率.曾报道儿童急性心肌炎患者,血清中度升高的cTnT浓度为0.088ng/ml(0.04～3.11ng/ml).该研究的目的在于确定诊断儿童急性心肌炎,且其特异性和敏感性均高的血清cTnT浓度值的下限.
Cardiac troponin T (cTnT) is a cardiomyocyte contractor with a relative molecular mass of 39000. It is a meager filamentous subunit structure that is highly specific and sensitive to myocardial damage in children. In severe myocardial infarction 3 to 4 days after injury, elevated blood levels, and to maintain this high level of 6 to 14 days can be used as a serum marker of acute myocarditis, and may indicate the incidence of myocarditis and mortality rates have been reported in children with acute myocarditis , And a moderate serum cTnT concentration of 0.088 ng / ml (0.04 to 3.11 ng / ml) .The purpose of this study was to determine the lower limit of the serum cTnT concentration value for the diagnosis of acute myocarditis in children with high specificity and sensitivity .