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目的 探讨卡维地洛治疗慢性充血性心力衰竭 (CHF)的临床疗效。方法 采用随机自身对照及组间对照 ,将 70例CHF病人随机分为治疗组和对照组 ,两组均给予常规抗心衰治疗 ,治疗组加用卡维地洛治疗 3个月。结果 治疗组治疗前后心率、血压、心功能、左室射血分数 (LVEF)、左室舒张末期容积 (EDV)、左室收缩末期容积 (ESV)均有显著改善 (P <0 0 0 1)。结论 在常规抗心衰药物治疗基础上加用卡维地洛可明显改善心功能 ,提高病人生存率。
Objective To investigate the clinical efficacy of carvedilol in the treatment of chronic congestive heart failure (CHF). Methods Randomized self-control and inter-group comparison, 70 CHF patients were randomly divided into treatment group and control group, both groups were given conventional anti-heart failure treatment, the treatment group with carvedilol for 3 months. Results The heart rate, blood pressure, cardiac function, left ventricular ejection fraction (LVEF), left ventricular end-diastolic volume (EDV) and left ventricular end-systolic volume (ESV) were significantly improved in the treatment group before and after treatment (P <0.01) . Conclusion The use of carvedilol on the basis of conventional anti-heart failure drug therapy can significantly improve cardiac function and improve patient survival rate.