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采用气管注入染尘技术探讨了碳纤维复合材料（ＣＦＣ）粉尘对大鼠肺的致纤维化作用，另设石英（阳性对照）和二氧化钛（阴性对照）组与之比较。结果表明：染ＣＦＣ粉尘大鼠肺脏初期病变为异物性肉芽肿反应，后期ＣＦＣ粉尘在肺内形成黑色斑块，但无纤维组织增生，斑块周围肺泡明显扩张，肺纤维化反应的强度与二氧化钛粉尘接近。其病变特征又类似于碳素性粉尘，唯纤维化程度比其轻。所获结果为制订ＣＦＣ粉尘卫生标准提供了实验依据。
The effects of carbon fiber composite (CFC) dust on lung fibrosis in rats were investigated by tracheal injection of dust, compared with the quartz (positive control) and titanium dioxide (negative control) groups. The results showed that the initial pathological changes of lung in CFC dust-exposed rats were foreign granuloma. The late-stage CFC dust formed black plaques in the lungs, but no fibrous tissue hyperplasia, obvious alveolar expansion around the plaque. The intensity of pulmonary fibrosis reaction was similar to that of titanium dioxide Dust close. Its lesion characteristics are similar to carbon dust, the degree of fiber-only lighter than it. The results obtained for the development of CFC dust health standards provide an experimental basis.