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目的探讨新疆哈萨克族食管癌发病的危险因素。方法采用1∶2配比的病例对照研究方法,调查92例食管癌患者、184名正常对照。采用条件Logistic回归模型进行分析。结果单因素分析显示,职业为牧民、饮用手压机井水、河水、大量饮酒、喜辣食、食速快、不规律、有食管、胃病变史及食管癌家族史等因素与食管癌的发生有关;多因素Cox回归分析显示,饮用手压机井水或河水、有食管癌家族史、辛辣饮食及食速快为食管癌发生的主要危险因素,食用新鲜水果为保护因素。结论改善饮水条件,改变不良饮食生活习惯,经常食用新鲜蔬菜和水果,可减少哈萨克族食管癌发生的危险性。
Objective To explore the risk factors of Kazakh esophageal cancer in Xinjiang. Methods A case-control study with a ratio of 1: 2 was used to investigate 92 patients with esophageal cancer and 184 normal controls. Logistic regression model was used to analyze. Results Univariate analysis showed that occupations for the herdsmen, hand drinkers drinking well water, river water, a large number of drinking, hi spicy food, fast food, irregular, with esophageal and gastric disease and family history of esophageal cancer and other factors and esophageal cancer The multivariate Cox regression analysis showed that drinking hand-pressure well water or river water had a family history of esophageal cancer, spicy diet and fast food esophageal cancer were the main risk factors, consumption of fresh fruits as a protective factor. Conclusions Improving drinking water conditions, changing bad diet habits and regular consumption of fresh vegetables and fruits can reduce the risk of Kazakh esophageal cancer.