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目的调查研究四川省偏远地区居民的血脂水平和踝臂指数(ABI)。方法同济大学医学院心肺血管中心自2005年7月6日至25日选取四川攀枝花地区1个城镇及2个乡村的25～50岁的居民516名,空腹抽血测定血脂,并测量其ABI,然后对有效数据进行统计学处理。结果乡村居民的血浆总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白胆固醇(LDL-C)水平明显低于城镇居民,分别为(4.29±0.80)mmol/L对(3.88±0.83)mmol/L,(2.14±2.18)mmol/L对(1.66±1.05)mmol/L,(2.06±0.56)mmol/L对(1.94±0.59)mmol/L,均P0.05,其中乡村居民的LDL-C平均值明显低于ATPⅢ建议的冠心病或冠心病等危症的LDL-C治疗目标值2.6mmol/L。两地区部分居民的HDL-C水平属于1997年我国的《血脂异常防治指南》建议的“合适范围”,但其差异无统计学意义[(1.44±0.41)mmol/L对(1.42±0.35)mmol/L,P=0.623]。两地区居民的ABI平均值均大于0.9,且乡村居民的ABI明显高于城镇居民(1.07±0.12对1.03±0.12,P=0.001)。结论饮食习惯和体力劳动可能明显降低体内TC、LDL-C和TG水平,高胆固醇所致的动脉硬化性疾病也较少发生。
Objective To investigate the blood lipid levels and the ankle brachial index (ABI) of residents in remote areas of Sichuan Province. Methods A total of 516 25- to 50-year-old residents from 1 town and 2 villages in Panzhihua, Sichuan Province were selected from July 6 to 25, 2005. The blood lipids were measured by fasting and the ABI was measured. Then valid data are statistically processed. Results The levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in rural residents were significantly lower than those in urban residents (4.29±0.80 mmol/L vs. 3.88±0.83, respectively). ) mmol/L, (2.14±2.18) mmol/L vs. (1.66±1.05) mmol/L, (2.06±0.56) mmol/L vs. (1.94±0.59) mmol/L, all P<0.05, of which rural residents The LDL-C mean value was significantly lower than the ATP III recommended coronary heart disease or coronary heart disease risk of LDL-C treatment target value of 2.6mmol/L. The HDL-C levels of some residents in the two regions belong to the “appropriate range” suggested by the “Guidelines for the prevention and treatment of dyslipidemia” in China in 1997, but the difference was not statistically significant [(1.44±0.41) mmol/L vs. (1.42±0.35) mmol /L, P=0.623]. The average ABI of residents in both regions was greater than 0.9, and the ABI of rural residents was significantly higher than that of urban residents (1.07±0.12 vs. 1.03±0.12, P=0.001). Conclusion Eating habits and manual labor may significantly reduce the level of TC, LDL-C and TG in the body, and arteriosclerotic diseases caused by high cholesterol also occur less often.