胰十二指肠切除术(pancreaticoduodenectomy,PD)是治疗胰头癌及壶腹周围癌的经典术式。但由于手术时间长、涉及多个重要器官联合切除及消化道重建等诸多问题,术后易发生诸多并发症,其中最严重的并发症之一就是胰肠吻合口瘘(下称胰瘘)。据文献报道胰瘘发生率为5%～40%[1],由 Pancreaticoduodenectomy (PD) is a classic procedure for the treatment of pancreatic cancer and periampullary cancer. However, due to the long operation, involving a number of important organs and resection of the digestive tract reconstruction and many other problems, many complications are likely to occur after surgery, one of the most serious complications of pancreaticojejunostomy fistula (hereinafter referred to as pancreatic fistula). According to the reported incidence of pancreatic fistula 5% to 40% [1], from