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目的:探讨和分析新生儿听力筛查中假阳性的发生率和原因并研究应对措施。方法:应用畸变产物耳声发射(DPOAE)和脑干听觉诱发电位(ABR)对2009年07月至2010年07月在我院的新生儿1076例进行听力筛查,其中产科出生的正常新生儿680例,新生儿科住院的高危新生儿396例。初筛时间为生后3天,用DPOAE进行,复筛应用DPOAE联合ABR于生后42天进行。复筛仍未通过者,于生后3个月转上级医院行听力诊断性检查,评估听力水平,并继续跟踪随访。结果:产科正常新生儿组初筛通过率95.15%,假阳性率4.71%,复筛总通过率99.85%;新生儿科高危儿组初筛通过率90.15%,假阳性率8.59%,复筛总通过率98.74%。结论:健康状况对新生儿听力初筛有影响,DPOAE联合ABR进行筛查可减少假阳性率。
Objective: To investigate and analyze the incidence and causes of false positives in neonatal hearing screening and to study the countermeasures. Methods: 1076 newborns in our hospital from July 2009 to July 2010 were subjected to hearing screening with Distortion Product Otoacoustic Emission (DPOAE) and Brainstem Auditory Evoked Potential (ABR). Among them, normal neonates 680 cases, 396 cases of neonatal high-risk neonates hospitalized. The screening time was 3 days after birth, with DPOAE, DPOAE combined with ABR rescreening 42 days after birth. The patients who failed to pass the screening were transferred to the higher level hospitals for diagnostic tests to assess their hearing levels and to follow up the follow-up three months after birth. Results: The screening rate of normal newborn infants was 95.15%, the false positive rate was 4.71%, and the total re-screening rate was 99.85%. The screening rate of 90.15% and the false positive rate of the high-risk group were 8.59% Rate of 98.74%. Conclusion: The health condition has an impact on the neonatal hearing screening, DPOAE screening combined with ABR can reduce the false positive rate.