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目的讨论神经皮肤黑变病(NCM)合并部分性癫的手术治疗及效果。方法回顾性分析1例NCM合并癫病人的临床资料。皮质电极监测后,行颞极及颞叶新皮质部分切除术。结果术后脑组织病理提示:颞极见大量黑色素细胞,原发性脑膜黑色素细胞增生症。皮肤病理提示复合性色素痣。术后10个月无癫发作。Engel分级Ⅰ级。结论 NCM是癫的罕见原因,但手术治疗效果满意。致灶切除术是一种安全有效的治疗方法。
Objective To discuss the surgical treatment and effect of neurocutaneous melanosis (NCM) with partial epilepsy. Methods The clinical data of 1 patient with NCM combined with epilepsy were retrospectively analyzed. After cortical electrode monitoring, the temporal pole and temporal cortex neo-cortex partial resection. Results Postoperative brain histopathology suggests that there are a large number of melanocytes in the temporal electrode and primary melanocytic hyperplasia. Skin pathology suggestive of complex pigmented nevus. No epileptic seizures occurred 10 months after surgery. Engel grade Ⅰ. Conclusion NCM is a rare cause of epilepsy, but the effect of surgery is satisfactory. To stovepipectomy is a safe and effective treatment.