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1980～1988年收治22例卵巢内胚窦瘤,按术后残存肿瘤<1cm和>1cm分成两组,两组分别存活期各为46个月和15.5个月(P<0.01).又按术后予以联合化疗和单一化疗分成两组,两组存活期分别为28个月和10个月(P<0.05).术后首先应用腹腔联合化疗,越早越好.DDP和5—Fu联合腹腔化疗较合理,3次后每月1次VAC方案全身化疗效果较佳.少数病例在7～8个疗程后加全腹~(60)Co外照射.早期病例应行腹膜后淋巴清除术.连续测定AFP可作为治疗监护和评价预后.不宜行二次探查术.
Twenty-two cases of ovarian endodermal sinus tumor were treated in 1980 ~ 1988 and divided into two groups according to residual tumor <1cm and> 1cm after operation. The two groups survived for 46 months and 15.5 months respectively (P <0.01) Combined chemotherapy and chemotherapy were divided into two groups, the survival of the two groups were 28 months and 10 months (P <0.05) .After the first application of intraperitoneal chemotherapy, the sooner the better.DDP and 5-Fu combined with abdominal cavity Chemotherapy is reasonable, after 3 times a month VAC regimen systemic chemotherapy better. A few cases of 7 to 8 courses plus full abdominal ~ (60) Co external irradiation. Early cases should be treated with retroperitoneal lymph node dissection. Determination of AFP can be used as treatment monitoring and evaluation of the prognosis.