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本文应用图像分析仪对有常规病理学检查的77例重症肝炎肝穿刺标本进行了坏死面积与临床关系的研究。结果显示,急重肝发病10天内肝穿刺标本坏死面积在存活与死亡组之间有明显差异,表明早期肝活检中坏死面积对预后估计价值较大。此外,还探讨了肝坏死面积与血清总胆红素(TB)及凝血酶原活动度(PTA)的关系,二者在一定范围内可以作为估计肝坏死量的间接指标。
In this paper, 77 cases of severe hepatitis liver biopsy specimens with routine pathological examination were studied by image analyzer for the necrotic area and the clinical relationship. The results showed that within 10 days of acute severe hepatic necrosis, the necrosis area of liver biopsy specimens was significantly different between survival and death groups, indicating that the necrosis area in early liver biopsy is of great value in prognosis. In addition, the relationship between hepatic necrosis area and serum total bilirubin (TB) and prothrombin activity (PTA) was also explored, both of which could be used as an indirect indicator to estimate the amount of hepatic necrosis within a certain range.