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目的:研究女性血清激素及血脂水平与围绝经期症状之间的关系。方法:选择2013年6月至2016年6月于中山市东升医院就诊的女性77例作为本研究对象,将其分为两组:围绝经期组(44例)与绝经后组(33例);测量两组的身高、体质量、血脂、血压、空腹血糖;前组于月经周期3~5 d检测雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T),后组检测时间随意。之后根据糖尿病学会代谢异常诊断标准将两组细化分为代谢异常组(观察组)与代谢正常组(对照组),比较观察组与对照组的E2、T、E2/T值。结果:绝经后组:观察组E2、E2/T值远低于对照组(P<0.05),围绝经期的两组比较,差异无统计学意义(P>0.05);绝经后组中的观察组E2、E2/T值明显低于围绝经期组中的观察组(P<0.05),T值比较,差异无统计学意义(P>0.05)。结论:围绝经期症状与雌雄激素比例失调、雌激素水平降低均有关系。
Objective: To study the relationship between serum levels of serum hormones and blood lipids and perimenopausal symptoms in women. Methods: Totally 77 female patients treated in Dongsheng Hospital of Zhongshan City from June 2013 to June 2016 were divided into two groups: perimenopausal group (44 cases) and postmenopausal group (33 cases) (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) and testosterone (E2) were measured in the first three days of the menstrual cycle in the menstrual cycle. The body weight, blood lipid, blood pressure and fasting blood glucose T), after the test group at random. Then according to the diagnostic criteria of diabetes mellitus metabolic abnormalities, the two groups were divided into metabolic abnormal group (observation group) and normal metabolic group (control group), and E2, T, E2 / T values between the observation group and the control group were compared. Results: In the postmenopausal group, the E2 and E2 / T values in the observation group were much lower than those in the control group (P <0.05). There was no significant difference in the perimenopausal group between the two groups (P> 0.05) The E2 and E2 / T values of the patients in the perimenopausal group were significantly lower than those in the perimenopausal group (P <0.05). There was no significant difference in the values of T between the two groups (P> 0.05). Conclusion: Perimenopausal symptoms and estrogen androgen imbalance, estrogen levels are related.