坏死性小肠结肠炎(necrotizingenterocolitis ,NEC)是新生儿最常见的胃肠急症。自1975年以来,通过流行病学调查、临床和实验研究已逐渐了解其致病原因和发病机理。发病率由于各地区、研究所间,年份不同及低出生体重儿存活数等计算上的差异,目前难以查明。近年多个大的新生儿中 Necrotizing enterocolitis (necrotizingenterocolitis, NEC) is the most common gastrointestinal emergency in newborns. Since 1975, through epidemiological investigation, clinical and experimental studies have gradually understand its causative cause and pathogenesis. The morbidity is difficult to pinpoint due to the computational differences among regions, institutes, years of age and survival of low birth weight infants. In recent years, many large newborns