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近年来,心血管受体学说进展很快,许多新的受体激动剂与阻滞剂已广泛应用于临床。本文对心血管的α、β受体,5羟色胺、组织胺受体与多巴胺受休的有关情况作一综述。 心血管α与β受体 自1948年Ahlguist发现肾上腺素能α与β受体以后,人们已确定这两种受体在血管平滑肌上的存在,并对其功能的认识不断加深。对于心肌细胞膜过去认为只有β受体,但最近发现也存在α受体。α受体为α_1与α_2两种,通常α_1受体分布于突触后膜;α_2受体分布于突触前膜,但少数α_2受体也分
In recent years, cardiovascular receptor theory has progressed rapidly, many new receptor agonists and blockers have been widely used in clinical. This review summarizes the cardiovascular related effects of α, β receptors, serotonin, histamine receptors and dopamine disruption. Cardiovascular Alpha and Beta Receptors Since the discovery of adrenergic alpha and beta receptors by Ahlguist in 1948, the existence of these two receptors on vascular smooth muscle has been identified and their understanding of their function deepened. Myocardial cell membranes were thought to have only beta receptors in the past, but alpha receptors have recently been found. α receptors are α_1 and α_2 two kinds, usually α_1 receptors distributed in the postsynaptic membrane; α_2 receptors distributed in the presynaptic membrane, but also a small number of α_2 receptors